Sepsis-induced alterations in sleep of rats.

Title: Sepsis-Induced Alterations in Sleep of Rats

Sepsis is a systemic immune response to infection that may result in multiple organ failure and death. Polymicrobial infections remain a serious clinical problem, and in the hospital sepsis is the number one non-cardiac killer. Although the central nervous system may be one of the first systems affected, relatively little effort has been made to determine the impact of sepsis on the brain. In t...

Effect of Acute and Chronic Heat Exposure on Frequency of EEG Components in Different Sleep-Wake State in Young Rats

The recent literatures indicate that central nervous system (CNS) is highly vulnerable to systemic hyperthermia induced by whole body heating on conscious animals. In the present study, cerebral electrical activity or EEG (electroencephalogram) following exposure to high environmental heat has been studied in moving rats. Rats were divided into three group (i) acute heat stress-subjected to a s...

Comparative evaluation of the therapeutic effects of silymarin and hydrocortisone on clinical and hematological alterations, and organ injury (liver and heart) in low-dose canine lipopolysaccharide-induced sepsis model

The present study aimed to examine the effectiveness of silymarin compared to hydrocortisone on clinical and hematological alterations and organ injury (liver and heart) in a low-dose canine lipopolysaccharide (LPS)-induced sepsis model. Fifteen clinically healthy dogs were randomly categorized into three equal groups: Two dogs in group A, LPS (0.10 μg kg-1, IV) was injected (control...

Sulpiride-Induced Hyperprolactinemia in Mature Female Rats: Evidence for Alterations in The Reproductive System, Pituitary and Ovarian Hormones

Caffeine attenuates paradoxical sleep deprivation induced- memory impairment during paradoxical sleep windows in rats

There is considerable evidence to support the hypothesis of relationship between paradoxical sleep (PS) and learning–memory processing. It has been suggested that PS is important in memory retention at the specific time course called PS windows (PSW). The time of PSWs occurrence and duration of these PSWs following the training sessions and, the neurochemical nature of PSWs has not been well kn...